By Ying Deng, Wei Lv
Biofilms and Implantable scientific units: an infection and Control explores the expanding use of everlasting and semi-permanent implants and indwelling clinical units. As an realizing of the expansion and impression of biofilm formation on those clinical units and biomaterials is essential for safeguarding the health and wellbeing of the human host, this e-book offers readers with a finished treatise on biofilms and their dating with clinical units, additionally reporting on infections and linked suggestions for prevention.
- Provides precious info at the basics of biofilm difficulties in scientific devices
- Discusses biofilm difficulties in more than a few scientific devices
- Focuses on innovations for prevention of biofilm formation
Read or Download Biofilms and Implantable Medical Devices. Infection and Control PDF
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Additional info for Biofilms and Implantable Medical Devices. Infection and Control
Oralis, associated with early bacterial adhesion, and Porphyromonas gingivali. Dorigatti et al studied the formation of biofilms on different implant abutment materials, such as zirconia and titanium. They showed in an in vitro study that both physical and chemical characteristics of the materials affect the adhesion and the biofilm formation. , 2015). , 2016). The properties of materials, such as surface polarity, can develop electrostatic energy and help the formation of different biofilms. It is well known that biomaterials with lower surface free energy (zirconium) inhibit the attachment of bacteria.
Structural and quantitative analysis of a mature anaerobic biofilm on different implant abutment surfaces. J. Prosthet. Dent. 114. , 2009. Methanogenic archaea in health and disease: a novel paradigm of microbial pathogenesis. Int. J. Med. Microbiol. 299 (2), 99–108. , 2002. Biofilms: survival mechanisms of clinically relevant microorganisms. Clin. Microbiol. Rev. 15, 167–193. , 2013. Candida biofilms and their role in infection. Trends Microbiol. 11, 30–36. , 2002. Pseudomonas biofilm formation and antibiotic resistance are linked to phenotypic variation.
In these situations, protease treatment is able to disintegrate the biofilms, usually incompletely. In S. aureus, protease-mediated biofilm detachment is controlled by quorum sensing (QS) signaling system. Another approach to generate the detachment of the biofilm relies on the production and release of small peptides (phenol-soluble modulins (PSMs), which were first described as proinflammatory agents in S. epidermidis (Heilmann and Gӧtz, 2009). Less common but dangerous, Finegoldia magna is a Gram-positive species involved in numerous infections of skin, bone, and joint tissues, grafts/prostheses, as well as synthetic valves.