By L. Garrido, J. Brey, R.B. Jones
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Extra info for Critical Phenomena
This is consistent with the observation that mitochondria-less yeast grow at a rate half that of Ethanol + * Growth rate s as om Bi Fig. 3 Schematic illustration of metabolic space. Hypothetical metabolic space bounded by growth rate, ethanol production and biomass production. Organism represented by “O” has optimized high ethanol production and biomass production but low growth rate, “*” has optimized high growth rate but low biomass and ethanol production while “+” has optimized high ethanol and biomass and growth rate.
The use of ATP is similar to the use of a common currency for financial transactions regardless of the source of wealth. There are other energy-rich molecules such as creatinine phosphate that serve a similar role as ATP but they are not as ubiquitous. ATP is not a storehouse of energy, but is used as a rechargeable battery. ATP links energy-yielding reactions to cellular processes that need energy input. For example, although glucose contains chemical energy, it cannot be used for muscular contraction, but ATP can.
During the course of these investigations, he also identified yeast strain unable to use galactose. By the turn of the 20th century, similar observations were rediscovered in bacteria. Henning Karstrome invoked the idea of enzyme adaptation to explain the delay in acclimatization when microbes start utilizing alternate carbon sources. He referred to enzymes existing in a living cell regardless of the nature of the nutrients present in the medium as “constitutive” while those formed only in the presence of their pathway substrate such as galactose as “adaptive”.